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Postoperative delirium

Delirium is a frequent occurrence after neurosurgery with older age, longer ICU stay, and a neurologic deficit being consistent risk factors across inpatient settings 1).

Postoperative delirium in spine surgery

Postoperative delirium in spine surgery.

A study identified the risk factors for postoperative delirium (PODE) in patients undergoing microvascular decompression (MVD) for the treatment of primary cranial nerve disorders.

He et al., retrospectively reviewed the data of 912 patients (354 men, 558 women) with primary cranial nerve disorders (trigeminal neuralgia, 602 patients; hemifacial spasm, 296 patients; glossopharyngeal neuralgia, 14 patients) who underwent MVD in the Neurosurgery Department of Lanzhou University Second Hospital between July 2007 and June 2018. Potential risk factors for PODE were identified using univariate and multivariate stepwise logistic regression analysis.Of the 912 patients, 221 (24.2%) patients developed PODE. Patients with PODE were significantly older and significantly more likely to be male than patients without PODE. A history of hypertension, preoperative carbamazepine therapy, and postoperative sleep disturbance and tension pneumocephalus were independently associated with PODE. Variables such as body-mass index, smoking and drinking habits, cardiac disease, diabetes mellitus, cerebrovascular disease, mean operative time, affected vessel, mean blood loss, postoperative intensive care unit stay, postoperative fever (>38°C), and routine laboratory results were not associated with PODE in there patients.PODE is a common complication after MVD, and is associated with multiple risk factors, including old age, male sex, hypertension, preoperative carbamazepine use, postoperative sleep disturbance, and tension pneumocephalus 2).


Morshed RA, Young JS, Safaee M, Sankaran S, Berger MS, McDermott MW, Hervey-Jumper SL. Delirium Risk Factors and Associated Outcomes in a Neurosurgical Cohort: A Case-Control Study. World Neurosurg. 2019 Mar 11. pii: S1878-8750(19)30624-2. doi: 10.1016/j.wneu.2019.03.012. [Epub ahead of print] PubMed PMID: 30872201.
He Z, Cheng H, Wu H, Sun G, Yuan J. Risk factors for postoperative delirium in patients undergoing microvascular decompression. PLoS One. 2019 Apr 18;14(4):e0215374. doi: 10.1371/journal.pone.0215374. eCollection 2019. PubMed PMID: 30998697.
postoperative_delirium.txt · Last modified: 2020/02/14 21:16 by administrador