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postsurgical_electrical_stimulation [2019/08/23 08:22]
postsurgical_electrical_stimulation [2019/08/23 08:24] (current)
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 +====== Postsurgical electrical stimulation ======
 +Patients with severe [[cubital tunnel syndrome]] often have poor [[functional recovery]] with conventional surgical treatment. Postsurgical electrical stimulation (PES) has been shown to enhance [[axon]]al [[regeneration]] in animal and human studies.
 +To determine if PES following surgery for severe cubital tunnel syndrome would result in better outcomes compared to surgery alone.
 +Patients with severe cubital tunnel syndrome in this [[randomized]],​ double-blind,​ placebo-controlled trial were randomized in a 1:2 ratio to the control or stimulation groups. Control patients received cubital tunnel surgery and sham stimulation,​ whereas patients in the stimulation group received 1-h of 20 Hz PES following surgery. Patients were assessed by a blinded evaluator annually for 3 yr. The primary outcome was motor unit number estimation (MUNE) and secondary outcomes were grip and key pinch strength and McGowan grade and compound muscle action potential.
 +A total of 31 patients were enrolled: 11 received surgery alone and 20 received surgery and PES. Three years following surgery, MUNE was significantly higher in the PES group (176 ± 23, mean + SE) compared to controls (88 ± 11, P < .05). The mean gain in key pinch strength in the PES group was almost 3 times greater than in the controls (P < .05). Similarly, other functional and physiological outcomes showed significantly greater improvements in the PES group.
 +[[Postsurgical electrical stimulation]] enhanced muscle [[reinnervation]] and functional [[recovery]] following surgery for severe [[cubital tunnel syndrome]]. It may be a clinically useful adjunct to surgery for severe [[ulnar neuropathy]],​ in which functional recovery with conventional treatment is often suboptimal
 +((Power HA, Morhart MJ, Olson JL, Chan KM. Postsurgical Electrical Stimulation
 +Enhances Recovery Following Surgery for Severe Cubital Tunnel Syndrome: A
 +Double-Blind Randomized Controlled Trial. Neurosurgery. 2019 Aug 20. pii: nyz322.
 +doi: 10.1093/​neuros/​nyz322. [Epub ahead of print] PubMed PMID: 31432080.
postsurgical_electrical_stimulation.txt · Last modified: 2019/08/23 08:24 by administrador