Remote ischemic conditioning

Remote ischemic conditioning (RIC) is an experimental medical procedure that aims to reduce the severity of ischaemic injury to an organ such as the heart or the brain, most commonly in the situation of a heart attack or a stroke, or during procedures such as heart surgery when the heart may temporary suffer ischemia during the operation, by triggering the body's natural protection against tissue injury.

Although noted to have some benefits in experimental models in animals, this is still an experimental procedure in humans and initial evidence from small studies has not been replicated in larger clinical trials. Successive clinical trials have failed to identify evidence supporting a protective role in humans.

One-time RIC interventions may show seemingly coexisted proinflammatory and anti-coagulation effects of a single bout on patients with cerebral arteriostenosis. Older age was a negative predictor for multiple biomarkers in the cerebral arteriostensosis group. The protective effect of RIC on cerebral venostenosis patients needs to be further studied in a larger sample size 1).

Song SY, Jiao BL, Lan D, Liu YH, Wan SL, Guo YB, Ding YC, Ji XM, Meng R. Potential Anti-Inflammatory and Anti-Coagulation Effects of One-Time Application of Remote Ischemic Conditioning in Patients With Subacute/Chronic Cerebral Arteriostenosis and Venostenosis. Neurologist. 2022 Jun 8. doi: 10.1097/NRL.0000000000000425. Epub ahead of print. PMID: 35680386.
  • remote_ischemic_conditioning.txt
  • Last modified: 2022/06/10 12:49
  • by administrador