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Single center study

Practice guidelines should rarely, if ever, be based on evidence from single-center clinical trials. Physicians should apply the findings of single-center trials only after careful evaluation of their methodology, and in particular after comparing the context of the trial with their own situation 1).

Bellomo R, Warrillow SJ, Reade MC. Why we should be wary of single-center trials. Crit Care Med. 2009 Dec;37(12):3114-9. doi: 10.1097/CCM.0b013e3181bc7bd5. Review. PubMed PMID: 19789447.
single_center_study.txt · Last modified: 2016/06/25 18:59 (external edit)