suboccipital_decompressive_craniectomy_for_cerebellar_infarction

Suboccipital Decompressive Craniectomy for cerebellar infarction

https://docs.google.com/presentation/d/1trLkGq-T7VrwpftyBeHneOgxRWKyM2QyF4uoeKO5aVU/edit?usp=sharing

Unlike the situation with supratentorial masses causing herniation, there are several reports of patients in a deep coma from direct brainstem compression who were operated upon quickly and made useful recovery.

Guidelines from the American Heart Association/Stroke Council’s Scientific Statement Oversight Committee from 2014 recommended suboccipital decompressive craniectomy (SDC) with dural expansion to be performed in deteriorating patients with cerebellar infarction failing maximal medical therapy 1).

However, no good-quality evidence is available to support this surgical practice, and the surgical timing and technique both remain controversial 2).

The evidence favoring suboccipital decompressive craniectomy in space-occupying cerebellar infarctions stems predominantly from retrospective, monocentric, uncontrolled studies. 3).


Large multicenter RCTs are lacking for this situation probably due to the well-known devastating effects of brainstem compression and hydrocephalus.

Criteria for patient selection and the timing of the operation are not yet established, although there are several reports that DSC is effective


For Suyama et al. early suboccipital decompressive craniectomy should be considered for treating cerebellar infarction in patients with GCS 13 or worse. A poor prognosis is inevitable in patients whose infarction is combined with other locations than the cerebellum but in those who already have obstructive hydrocephalus at the time of surgery 4).

The operation of choice is a suboccipital decompression to include enlargement of the foramen magnum. The dura is then opened and the cerebellar infarction tissue usually exudes “like toothpaste” and is easily aspirated. Avoid using ventricular drainage alone as this may cause upward cerebellar herniation and does not relieve the direct brainstem compression.


The patient is positioned prone on chest rolls with the head in a Mayfield head-holder or in a horseshoe headrest. Flex the neck to open the interspace between the occiput and posterior arch of C1. The shoulders is retracted inferiorly with adhesive tape. A midline skin incision from inion to ≈ C2 spinous process is made.

Open the dura in a “Y” shaped incision, and excise the triangular top flap.


Necrosectomy appears to be a suitable alternative, achieving comparable mortality and functional outcomes. Further trials are necessary to evaluate which surgical technique is more beneficial 5).

Suboccipital decompressive craniectomy (SDC) for cerebellar infarction has been traditionally performed with minimal high-quality evidence. The aim of a systematic review and meta-analysis from the UBC Hospital, Vancouver, was to investigate the impact of SDC on functional outcomes, mortality, and adverse events in patients with cerebellar infarctions.

A systematic review and meta-analysis in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and MetaAnalyses) guidelines. The primary outcome was the proportion of patients with a moderate-severe disability after SDC. Secondary outcomes included mortality and adverse events. A sensitivity analysis was conducted to examine the roles of age, preoperative neurologic status, external ventricular drain insertion, and debridement of infarcted tissue on SDC outcomes.

Eleven studies (with 283 patients) met the inclusion criteria. The pooled event rate for moderate-severe disability was 28% (95% confidence interval [CI], 20%-37%) and for mortality, it was 20% (95% CI, 12%-31%). The estimated overall rate of adverse events for SDC was 23% (95% CI, 14%-35%).Sensitivity analysis found less mortality with mean age <60 years, higher rates of concomitant external ventricular drain insertion, and debridement of infarcted tissue. Several factors were identified for heterogeneity between studies, including follow-up time, outcomes scale, extent of infarction, and other neuroimaging features.

The best available evidence for SDC is based on retrospective observational studies. SDC for cerebellar infarction is associated with better outcomes compared with decompressive surgery for hemispheric infarctions. Lack of standardized reporting methods for SDC is a considerable drawback to the development of a better understanding of the impact of this surgery on patient outcomes 6).

cerebellar infarction and associated brain edema due to brainstem compression or obstructive hydrocephalus cause consciousness disturbance. In such cases, the mortality rate is reported to be 84% 7) when decompressive suboccipital craniectomy (DSC) is not performed


The best available evidence for Suboccipital Decompressive Craniectomy is based on retrospective observational studies. SDC for cerebellar infarction is associated with better outcomes compared with decompressive surgery for hemispheric infarctions. Lack of standardized reporting methods for SDC is a considerable drawback to the development of a better understanding of the impact of this surgery on patient outcomes 8).


A poor prognosis is inevitable in patients whose infarction is combined with other locations than the cerebellum but in those who already have obstructive hydrocephalus at the time of surgery 9).


Brainstem infarction and bilateral cerebellar infarction were associated with unfavorable outcome 10).


Favorable clinical outcomes including overall survival can be expected after preventive Suboccipital Decompressive Craniectomy in patients with a volume ratio between 0.25 and 0.33 and the absence of brainstem infarction. Among these patients, preventive Suboccipital Decompressive Craniectomy might be better than the best medical treatment alone 11).

Suboccipital Decompressive Craniectomy for cerebellar infarction Case series.

Suboccipital Decompressive Craniectomy for cerebellar infarction Case reports.


1)
Wijdicks EF, Sheth KN, Carter BS, Greer DM, Kasner SE, Kimberly WT, Schwab S, Smith EE, Tamargo RJ, Wintermark M; American Heart Association Stroke Council. Recommendations for the management of cerebral and cerebellar infarction with swelling: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014 Apr;45(4):1222-38. doi: 10.1161/01.str.0000441965.15164.d6. Epub 2014 Jan 30. PubMed PMID: 24481970.
2) , 5)
Hernández-Durán S, Wolfert C, Rohde V, Mielke D. Cerebellar Necrosectomy Instead of Suboccipital Decompression: A Suitable Alternative for Patients with Space-Occupying cerebellar infarction. World Neurosurg. 2020 Dec;144:e723-e733. doi: 10.1016/j.wneu.2020.09.067. Epub 2020 Sep 22. PMID: 32977029.
3)
Neugebauer H, Witsch J, Zweckberger K, Jüttler E. Space-occupying cerebellar infarction: complications, treatment, and outcome. Neurosurg Focus. 2013 May;34(5):E8. doi: 10.3171/2013.2.FOCUS12363. PMID: 23634927.
4) , 9)
Suyama Y, Wakabayashi S, Aihara H, Ebiko Y, Kajikawa H, Nakahara I. Evaluation of clinical significance of decompressive suboccipital craniectomy on the prognosis of cerebellar infarction. Fujita Med J. 2019;5(1):21-24. doi: 10.20407/fmj.2018-010. Epub 2018 Dec 6. PMID: 35111496; PMCID: PMC8766232.
6)
Ayling OGS, Alotaibi NM, Wang JZ, Fatehi M, Ibrahim GM, Benavente O, Field TS, Gooderham PA, Macdonald RL. Suboccipital Decompressive Craniectomy for cerebellar infarction: A Systematic Review and Meta-Analysis. World Neurosurg. 2018 Feb;110:450-459.e5. doi: 10.1016/j.wneu.2017.10.144. Epub 2017 Dec 2. PMID: 29104155.
7)
Feely MP. cerebellar infarction. Neurosurgery. 1979 Jan;4(1):7-11. doi: 10.1227/00006123-197901000-00003. PMID: 450221.
8)
Ayling OGS, Alotaibi NM, Wang JZ, Fatehi M, Ibrahim GM, Benavente O, Field TS, Gooderham PA, Macdonald RL. Suboccipital Decompressive Craniectomy for cerebellar infarction: A Systematic Review and Meta-Analysis. World Neurosurg. 2018 Feb;110:450-459.e5. doi: 10.1016/j.wneu.2017.10.144. Epub 2017 Dec 2. PMID: 29104155.
10)
Lindeskog D, Lilja-Cyron A, Kelsen J, Juhler M. Long-term functional outcome after decompressive suboccipital craniectomy for space-occupying cerebellar infarction. Clin Neurol Neurosurg. 2018 Dec 1;176:47-52. doi: 10.1016/j.clineuro.2018.11.023. [Epub ahead of print] PubMed PMID: 30522035.
11)
Kim MJ, Park SK, Song J, Oh SY, Lim YC, Sim SY, Shin YS, Chung J. Preventive Suboccipital Decompressive Craniectomy for cerebellar infarction: A Retrospective-Matched Case-Control Study. Stroke. 2016 Oct;47(10):2565-73. doi: 10.1161/STROKEAHA.116.014078. Epub 2016 Sep 8. PMID: 27608818.
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