Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers.
Its usefulness in people infected by H. pylori is limited. It is used by mouth and rectally.
Common side effects include constipation. Serious side effects may include bezoar formation and encephalopathy. Use appears to be safe in pregnancy and breastfeeding.
How it works is unclear but is believed to involve binding to the ulcer and protecting it from further damage.