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tp53

Tumor protein p53

Tumor protein p53.

see TP53 mutation.

Whenever possible, appropriate molecular genetics should also be evaluated. Testing for IDH1 and/or IDH2 mutations should be done in all diffuse gliomas if possible. Other tests (e.g. 1p/19q codeletion or TP53 gene mutations) are done as appropriate.


see Medulloblastoma, SHH-activated, and TP53-mutant.

see Medulloblastoma, SHH-activated, and TP53-wildtype


Li-Fraumeni syndrome is usually caused by a germline mutation in the TP53 tumor suppressor gene on chromosome 17p13.

tp53.txt · Last modified: 2019/12/30 18:43 by administrador