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Trigeminal neuralgia

The facial pain syndrome known as trigeminal neuralgia was described more than 300 years ago 1).


Trigeminal neuralgia definition.


see Trigeminal neuralgia epidemiology.


see Trigeminal neuralgia classification.


see Trigeminal neuralgia pathogenesis.


see Trigeminal neuralgia pathophysiology.

Natural History

Typical trigeminal neuralgia caused by microvascular compression of the trigeminal nerve root in the posterior fossa may become transformed over time into atypical trigeminal neuralgia, if left untreated. This transformation involves change in the character of pain and development of sensory impairment. Two representative cases are presented to support this theory.

If the theory of progressive change in character of pain and degree of sensory impairment in the course of otherwise typical trigeminal neuralgia is correct, trigeminal neuralgia, atypical neuralgia, and trigeminal neuropathic pain may represent different degrees of injury to the trigeminal nerve, therefore comprising a continuous spectrum rather than discrete diagnoses 2).

Clinical Features

Trigeminal neuralgia clinical features.


Barrow Neurological Institute Pain Scale.

Barrow Neurological Facial Numbness Scale.

Slavin KV. Commentary: Development and Evaluation of a Preoperative Trigeminal Neuralgia Scoring System to Predict Long-Term Outcome Following Microvascular Decompression. Neurosurgery. 2019 Dec 9. pii: nyz540. doi: 10.1093/neuros/nyz540. [Epub ahead of print] PubMed PMID: 31813971.


Trigeminal neuralgia diagnosis.


see Trigeminal neuralgia treatment.


see Trigeminal neuralgia outcome.

Case series

see Trigeminal neuralgia case series.

Case reports

see Trigeminal neuralgia case reports.

Lewy FH: The first authentic case of major trigeminal neuralgia and some comments on the history of this disease. Ann Med Hist 10:247–250, 1938.
Burchiel KJ, Slavin KV. On the natural history of trigeminal neuralgia. Neurosurgery. 2000 Jan;46(1):152-4; discussion 154-5. Review. PubMed PMID: 10626945.
trigeminal_neuralgia.txt · Last modified: 2019/12/10 13:42 by administrador