Uncinate fasciculus

The uncinate fasciculus: connects the anterior temporal lobe to the inferior frontal gyrus. Damage can cause language dysfunction.

see also Left uncinate fasciculus.

The uncinate fasciculus UF was described even earlier by Reil (Reil, 1809), characterized as the hooked-shape fibers behind the insula.

Both inferior fronto-occipital fasciculus and uncinate fasciculus are crucial for the ventral intra-hemispheric transfer of information between the frontal cortex and the occipital, temporal and parietal cortices, and knowing their cortical terminations is fundamental for understanding their role in mediating language semantics 1).

Several critical structures are located medial and deep to the insula. The extreme capsule, claustrum, external capsule, and striatum are located deep to the central portion of the insula. The fibers of the motor cortex converging into the posterior limb of the internal capsule run immediately deep to the posterior segment of the superior periinsular sulcus. The uncinate fasciculus runs medial to the anterior portion of the superior periinsular sulcus.

Turken A. U., Dronkers N. F. (2011). The neural architecture of the language comprehension network: converging evidence from lesion and connectivity analyses. Front. Syst. Neurosci. 5:1 10.3389/fnsys.2011.00001
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