Ventriculoperitoneal shunt for idiopathic normal pressure hydrocephalus

On the basis of a multicentre prospective randomized trial it is to be recommended to treat patients with idiopathic normal pressure hydrocephalus with a shunt with an adjustable valve, preset at the highest opening pressure and lowered until clinical improvement or radiological signs of overdrainage occur although slower improvement and more shunt adjustments might be the consequence 1)

A permanent CSF diversion with a ventriculoperitoneal shunt (VPS) is a treatment option for patients with idiopathic normal pressure hydrocephalus. An improvement of symptoms is seen in 70% to 85% of patients after shunting 2).

Outcomes after ventriculoperitoneal shunting for idiopathic normal pressure hydrocephalus (INPH) are variable due to a lack of reliable, quantitative outcome data and inconsistent methods of selecting shunt candidates.

Delwel EJ, de Jong DA, Dammers R, Kurt E, van den Brink W, Dirven CM. A randomized trial of high and low-pressure level settings on an adjustable ventriculoperitoneal shunt valve for idiopathic normal pressure hydrocephalus: results of the Dutch evaluation programme Strata shunt (DEPSS) trial. J Neurol Neurosurg Psychiatry. 2013 Jul;84(7):813-7. doi: 10.1136/jnnp-2012-302935. Epub 2013 Feb 13. PMID: 23408069.
Shaw R, Everingham E, Mahant N, Jacobson E, Owler B. Clinical outcomes in the surgical treatment of idiopathic normal pressure hydrocephalus. J Clin Neurosci. 2016 Jul;29:81-6. doi: 10.1016/j.jocn.2015.10.044. Epub 2016 Feb 28. PMID: 26935749.
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  • Last modified: 2021/04/08 20:51
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