World Health Organization grade 3 meningioma
Mast cells (MCs) were present in as many as 90 % of all high grade meningiomas mainly found in the perivascular areas of the tumor. A correlation between peritumoral edema and MCs was found.
Accumulation of MCs in meningiomas could contribute to the aggressiveness of tumors and to brain inflammation that may be involved in the pathogenesis of additional disorders 1).
Treatment
1)
Polyzoidis S, Koletsa T, Panagiotidou S, Ashkan K, Theoharides TC. Mast cells
in meningiomas and brain inflammation. J Neuroinflammation. 2015 Sep
17;12(1):170. doi: 10.1186/s12974-015-0388-3. PubMed PMID: 26377554.